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Istituto di scienza dell'alimentazione

Torna all'elenco Contributi in rivista anno 2016

Contributo in rivista

Tipo: Articolo in rivista

Titolo: Pereskia aculeata Muller (Cactaceae) Leaves: Chemical Composition and Biological Activities

Anno di pubblicazione: 2016

Formato: Elettronico

Autori: Souza, Luceia Fatima; Caputo, Lucia; Inchausti De Barros, Ingrid Bergman; Fratianni, Florinda; Nazzaro, Filomena; De Feo, Vincenzo

Affiliazioni autori: Univ Salerno; Univ Rio Grande Sul UFRGS; CNR

Autori CNR:

  • FLORINDA FRATIANNI
  • FILOMENA NAZZARO

Lingua: inglese

Abstract: The aims of this work were to study the chemical composition of the essential oil from the leaves of Pereskia aculeata and to evaluate some biological activities of three leaf extracts. The phenolic content, antioxidant activity, and in vitro antimicrobial and antifungal activities were determined. The methanol extract showed antioxidant activity (EC50 7.09 mg/mL) and high polyphenols content (15.04 +/- 0.31 mg gallic acid equivalents (GAE)/g). The petroleum ether extract exhibited potent antibacterial activity against Escherichia coli, whereas the chloroform extract showed inhibitory activity against Bacillus cereus and Staphylococcus aureus. The petroleum ether and methanol extracts were more effective in inhibiting the growth of Aspergillus versicolor. The possible cytotoxicity of extracts on neuroblastoma SH-SY5Y cancer cell line and the influence on adenylate cyclase (ADCY) expression was also studied. P. aculeata chloroform extract showed antiproliferative activity with an IC50 value of 262.83 mu g/mL. Treatments of SH-SY5Y neuroblastoma cells with 100 mu g/mL of methanol extract significantly reduced ADCY1 expression.

Lingua abstract: inglese

Pagine totali: 12

Rivista:

International journal of molecular sciences MDPI Center,
Paese di pubblicazione:
Lingua: inglese
ISSN: 1422-0067

Numero volume: 17

Numero fascicolo: 9

DOI: 10.3390/ijms17091478

Referee: Sė: Internazionale

Stato della pubblicazione: Published version

Indicizzato da: ISI Web of Science (WOS) [000385525500104]

Parole chiave:

  • Pereskia aculeata
  • essential oil
  • leaf extracts
  • antioxidant activity
  • antibacterial activity
  • antifungal activity
  • cytotoxicity
  • adenylate cyclase (ADCY)

Strutture CNR:

 
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