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Istituto di scienza dell'alimentazione

Torna all'elenco Contributi in rivista anno 2016

Contributo in rivista

Tipo: Articolo in rivista

Titolo: Early Life Factors and Inter-Country Heterogeneity in BMI Growth Trajectories of European Children: The IDEFICS Study

Anno di pubblicazione: 2016

Formato: Elettronico

Autori: Boernhorst, Claudia; Siani, Alfonso; Russo, Paola; Kourides, Yannis; Sion, Isabelle; Molnar, Denes; Moreno, Luis A.; Rodriguez, Gerardo; Ben-Shlomo, Yoav; Howe, Laura; Lissner, Lauren; Mehlig, Kirsten; Regber, Susann; Bammann, Karin; Foraita, Ronja; Ahrens, Wolfgang; Tilling, Kate

Affiliazioni autori: 1 Leibniz Institute for Prevention Research and Epidemiology - BIPS, Bremen, Germany, 2 Unit of Epidemiology and Population Genetics, Institute of Food Sciences, National Research Council, Avellino, Italy, 3 Research and Education Institute of Child Health, Strovolos, Cyprus, 4 Department of Public Health, Ghent University, Ghent, Belgium, 5 Department of Pediatrics, University of Pécs, Pécs, Hungary, 6 GENUD (Growth, Exercise, Nutrition and Development) Research Group, Faculty of Health Sciences, University of Zaragoza, Zaragoza, Spain, 7 IIS Aragón (Aragon Health Research Institute), Zaragoza, Spain, 8 School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom, 9 MRC Integrative Epidemiology Unit at the University of Bristol, Bristol, United Kingdom, 10 Section for Epidemiology and Social Medicine, Department of Public Health and Community Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden, 11 School of Health and Welfare, Halmstad University, Halmstad, Sweden, 12 Institute for Public Health and Nursing Research (IPP), Faculty for Human and Health Sciences, University Bremen, Bremen, Germany, 13 Faculty of Mathematics and Computer Science, University of Bremen, Bremen, Germany

Autori CNR:


Lingua: inglese

Abstract: Background Starting from birth, this explorative study aimed to investigate between-country differences in body mass index (BMI) trajectories and whether early life factors explain these differences. Methods The sample included 7,644 children from seven European countries (Belgium, Cyprus, Germany, Hungary, Italy, Spain, Sweden) participating in the multi-centre IDEFICS study. Information on early life factors and in total 53,409 repeated measurements of height and weight from 0 to <12 years of age were collected during the baseline (2007/2008) and follow-up examination (2009/2010) supplemented by records of routine child health visits. Countryspecific BMI growth curves were estimated using fractional polynomial mixed effects models. Several covariates focussing on early life factors were added to the models to investigate their role in the between-countries differences. Results Large between-country differences were observed with Italian children showing significantly higher mean BMI values at all ages 3 years compared to the other countries. For instance, at age 11 years mean BMI values in Italian boys and girls were 22.3 [21.9;22.8; 99% confidence interval] and 22.0 [21.5;22.4], respectively, compared to a range of 18.4 [18.1;18.8] to 20.3 [19.8;20.7] in boys and 18.2 [17.8;18.6] to 20.3 [19.8;20.7] in girls in the other countries. After adjustment for early life factors, differences between country-specific BMI curves became smaller. Maternal BMI was the factor being most strongly associated with BMI growth (p<0.01 in all countries) with associations increasing during childhood. Gestational weight gain (GWG) was weakly associated with BMI at birth in all countries. In some countries, positive associations between BMI growth and children not being breastfed, mothers' smoking during pregnancy and low educational level of parents were found. Conclusion Early life factors seem to explain only some of the inter-country variation in growth. Maternal BMI showed the strongest association with children's BMI growth.

Lingua abstract: inglese

Pagine totali: 20


PloS one Public Library of Science
Paese di pubblicazione: Stati Uniti d'America
Lingua: inglese
ISSN: 1932-6203

Numero volume: 11

Numero fascicolo: 2

DOI: 10.1371/journal.pone.0149268

Referee: Sě: Internazionale

Stato della pubblicazione: Published version

Indicizzato da: ISI Web of Science (WOS) [000371276100050]

Parole chiave:

  • Early Life Factors; BMI; European; IDEFICS

URL: https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0149268

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