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Istituto di scienza dell'alimentazione

Torna all'elenco Contributi in rivista anno 2015

Contributo in rivista

Tipo: Articolo in rivista

Titolo: Role of quercetin as an alternative for obesity treatment: You are what you eat!

Anno di pubblicazione: 2015

Formato: Cartaceo

Autori: Nabavi S.F.; Russo G.L.; Daglia M.; Nabavi S.M.

Affiliazioni autori: Applied Biotechnology Research Center, Baqiyatallah University of Medical Sciences, P.O. Box 19395-5487, Tehran, Iran; Institute of Food Sciences, National Research Council, Avellino, 83100, Italy; Department of Drug Sciences, Medicinal Chemistry and Pharmaceutical Technology Section, University of Pavia, Italy

Autori CNR:

  • GIAN LUIGI RUSSO

Lingua: inglese

Abstract: Obesity is one of the most serious global health problems, which increases the risk of other different chronic diseases. The crucial role of oxidative stress in the initiation and progression of obesity leads to the hypothesis that antioxidants can be used as therapeutic agents for obesity treatment. Among antioxidants, much attention has been paid to polyphenols due to their negligible adverse effects. Among them, quercetin is one of the most common dietary antioxidants widely distributed in different plant materials, such as fruits, vegetables and cereals. Quercetin shows a wide range of biological and health-promoting effects, such as anticancer, hepatoprotective, antidiabetic, anti-inflammatory and antibacterial activities. Furthermore, quercetin has anti-obesity activity through mitogen-activated protein kinase and adenine monophosphate-activated protein kinase signaling pathways. In this study, we reviewed the available scientific reports concerning the beneficial role of quercetin against obesity with emphasis on its mechanisms of action.

Lingua abstract: inglese

Pagine da: 305

Pagine a: 310

Rivista:

Food chemistry Applied Science Publishers.
Paese di pubblicazione: Regno Unito
Lingua: inglese
ISSN: 0308-8146

Numero volume: 179

DOI: 10.1016/j.foodchem.2015.02.006

Referee: Sì: Internazionale

Stato della pubblicazione: Published version

Indicizzato da: Scopus [2-s2.0-84923320950]

Parole chiave:

  • Adenine monophosphate-activated protein kinase
  • Antioxidants
  • Mitogen-activated protein kinase
  • Obesity
  • Quercetin

URL: http://www.scopus.com/inward/record.url?eid=2-s2.0-84923320950&partnerID=q2rCbXpz

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