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Istituto di scienza dell'alimentazione

Torna all'elenco Contributi in rivista anno 2001

Contributo in rivista

Tipo: Articolo in rivista

Titolo: Past history of nephrolithiasis and incidence of hypertension in men: a reappraisal based on the results of the Olivetti Prospective Heart Study.

Anno di pubblicazione: 2001

Formato: Cartaceo

Autori: Strazzullo P, Barba G, Vuotto P, Farinaro E, Siani A, Nunziata V, Galletti F, Mancini M, Cappuccio FP.

Affiliazioni autori: Department of Clinical and Experimental Medicine, Unit of Clinical Genetics and Pharmacology, Hypertension and Mineral Metabolism, Federico II University Medical School, Naples, Italy

Autori CNR:

  • GIANVINCENZO BARBA
  • ALFONSO SIANI

Lingua: inglese

Abstract: BACKGROUND: We have previously reported that in the Olivetti Prospective Heart Study cohort the incidence of nephrolithiasis was higher in hypertensive participants than in normotensive ones. As the time sequence and the mechanisms underlying the association between nephrolithiasis and hypertension remain controversial, we further tested the hypothesis that in a cohort of normotensive males a history of nephrolithiasis predicts the development of future hypertension. METHODS: The analysis was conducted in 381 male workers at Olivetti who were normotensive at the baseline examination and who were re-examined 8 years later. RESULTS: A past history of nephrolithiasis is associated with an increased risk of hypertension of 1.96 (95% CI=1.25-3.07) relative to subjects with a negative history, after adjusting for age. CONCLUSION: In this 8-year follow-up study, a history of nephrolithiasis resulted in an increased risk of developing hypertension in the future. As the reverse was also true, as previously reported, a clear-cut time sequence, as well as the mechanisms linking these two conditions, remain to be identified.

Lingua abstract: inglese

Pagine da: 2232

Pagine a: 2235

Pagine totali: 4

Rivista:

Nephrology, dialysis, transplantation Oxford University Press
Paese di pubblicazione: Regno Unito
Lingua: inglese
ISSN: 0931-0509

Numero volume: 16

DOI: 10.1093/ndt/16.11.2232

Referee: Sė: Internazionale

Indicizzato da: PubMed [11682673]

Parole chiave:

  • hypertension
  • nephrolithiasis
  • population study

Strutture CNR:

Moduli:

Allegati: articolo pubblicato (application/pdf)

 
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