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Istituto di scienza dell'alimentazione

Torna all'elenco Contributi in rivista anno 2012

Contributo in rivista

Tipo: Articolo in rivista

Titolo: From sleep duration to childhood obesity--what are the pathways?

Anno di pubblicazione: 2012

Formato: Cartaceo

Autori: Börnhorst C, Hense S, Ahrens W, Hebestreit A, Reisch L, Barba G, von Kries R, Bayer O; IDEFICS Consortium.

Affiliazioni autori: BIPS, Bremen University; Istituto di Scienze dell'Alimentazione, CNR; IDEFICS Consortium

Autori CNR:


Lingua: inglese

Abstract: Sleep duration has been identified as risk factor for obesity already in children. Besides investigating the role of fat mass (FM), this study addressed the question whether endocrine mechanisms act as intermediates in the association between sleep duration and overweight/obesity. Within the framework of the IDEFICS study, the present research was conducted in 609 German resident children aged 2-9 years with information on fasting insulin, C-reactive protein and cortisol levels next to anthropometric measurements and parental questionnaires. Emphasising methodological aspects, an age-specific measure of sleep duration was derived to account for alteration in sleep duration during childhood/period of growth. Multivariate linear regression and quantile regression models confirmed an inverse relationship between sleep duration and measures of overweight/obesity. The estimate for the association of sleep duration and body mass index (BMI) was approximately halved after adjustment for FM, but remained significant. The strength of this association was also markedly attenuated when adjusting for insulin mainly for the upper BMI quantiles (Q80, ? = -0.36 vs. ? = -0.26; Q95, ? = -0.87 vs. ? = -0.47). Adjustment for cortisol and CrP did not yield this attenuation. Conclusion: The inverse relationship between sleep duration and BMI is mainly explained by the association between sleep duration and FM. Insulin may explain part of this association, in particular at the upper tail of the BMI distribution.

Lingua abstract: inglese

Pagine da: 1029

Pagine a: 1038

Pagine totali: 10


European journal of pediatrics Springer
Paese di pubblicazione: Germania
Lingua: multilingue
ISSN: 0340-6199

Numero volume: 171

Numero fascicolo: 7

DOI: 10.1007/s00431-011-1670-8

Referee: Ś: Internazionale

Indicizzato da: PubMed [22237400]

Strutture CNR:


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