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Istituto di scienza dell'alimentazione

Torna all'elenco Contributi in atti di convegno anno 2011

Contributo in atti di convegno

Tipo: Presentazione

Titolo: MALDI-TOF Mass Spectrometry for the Indentification of Bacteria

Anno di pubblicazione: 2011

Autori: Siciliano RA

Affiliazioni autori: Institute of Food Science and Technology, Italian National research Council (CNR)

Autori CNR:

  • ROSA ANNA SICILIANO

Lingua: inglese

Abstract: Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) is an emerging technology for rapid bacteria identification. Specific mass spectral profiles are obtained by directly analysing whole bacterial cells or suitable protein extracts. Mass spectra are used to perform searches in dedicated libraries by means of specific bioinformatics tools to achieve bacterial identification at the genus, species and, in some cases, subspecies level. The performance of MALDI-TOF MS is very attractive considering its accuracy, efficiency, rapidity and cost-effectiveness. Recent significant advancements of this technique, in terms of development of comprehensive software tools and widening of bacterial reference databases (which nowadays include mass spectra of thousand of bacterial species), let foresee its widespread use as a routine method for microbiological control in clinical, pharmacological, food and environmental fields.

Lingua abstract: inglese

Congresso nome: 2011 PDA Europe Conference Pharmaceutical Microbiology - Mycoplasma

Congresso luogo: Berlin

Congresso data: 15-18 March 2011

Congresso rilevanza: Internazionale

Congresso relazione: Su invito

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