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Istituto di fisiologia clinica

Torna all'elenco Contributi in rivista anno 2009

Contributo in rivista

Tipo: Articolo in rivista

Titolo: Exhaled air temperature in asthmatic children: a mathematical evaluation

Anno di pubblicazione: 2009

Formato: Elettronico Cartaceo

Autori: Pifferi M, Ragazzo V, Previti A, Pioggia G, Ferro M, Macchia P, Piacentini GL, Boner AL.

Affiliazioni autori: Department of Pediatrics, University of Pisa, Pisa; Interdepartmental Research Center ``E. Piaggio'', Faculty of Engineering, University of Pisa - Institute of Clinical Physiology CNR; Department of Pediatrics, University of Verona, Verona, Italy

Autori CNR:

  • GIOVANNI PIOGGIA

Lingua: inglese

Abstract: Recently, the exhaled breath temperature has been proposed as a potential marker for the evaluation of airway inflammation in asthma. The purpose of this study was to verify the ability to distinguish asthmatics from normal controls by a dedicated detailed mathematical evaluation of the exhaled air curve. Analysis was performed in the different phases of the curve of exhaled temperature, i.e. the rate of temperature increase (DeT) and the mean plateau value. Principal components analysis (PCA) and artificial neural networks (ANNs) were used for the evaluation of the data in 90 asthmatic children and in 33 healthy age-matched controls. Both PCA and ANNs showed that a separation between patients and controls can be obtained only by the evaluation of the plateau phase of the curve, which better reflects the periphery of the airway.

Lingua abstract: inglese

Pagine da: 164

Pagine a: 171

Rivista:

Pediatric allergy and immunology Blackwell
Paese di pubblicazione: Regno Unito
Lingua: inglese
ISSN: 0905-6157

Numero volume: 20

DOI: 10.1111/j.1399-3038.2008.00742.x

Referee: Sė: Internazionale

Parole chiave:

  • artificial neural networks
  • asthmatic children
  • Kohonen self-organizing maps
  • principal components analysis

Strutture CNR:

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