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Istituto di Farmacologia Traslazionale

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Elenco Contributi in rivista anno 2019

Di Bonito P1, Licenziati MR2, Di Sessa A3, Manco M4, Morandi A 5, Maffeis C5, Chiesa C6, Pacifico L7, Valerio G8.
A new simple formula built on the American Academy of Pediatrics criteria for the screening of hypertension in overweight/obese children.

Fuggetta M.P.; Spanu P.; Ulgheri F.; Deligia F.; Carta P.; Mannu A.; Trotta V.; Cicco R.D.; Barra A.; Zona E.; Morelli F.
A new synthetic spiroketal: Studies on antitumor activity on murine melanoma model in vivo and mechanism of action in vitro

Dettin, Monica; Sieni, Elisabetta; Zamuner, Annj; Marino, Ramona; Sgarbossa, Paolo; Lucibello, Maria; Tosi, Anna Lisa; Keller, Flavio; Campana, Luca Giovanni; Signori, Emanuela
A Novel 3D Scaffold for Cell Growth to Assess Electroporation Efficacy

Erica M. Briggs1, Corrado Spadafora3 and Susan K. Logan1,2
A re-evaluation of LINE-1 ORF2 expression in LNCaP prostate cancer cells

Lucia Pacifico 1,2 Francesco Massimo Perla 1 , Mario Roggini 1 , Gianmarco Andreoli 1,Miriam D'Avanzo 1 and Claudio Chiesa 2
A Systematic Review of NAFLD-AssociatedExtrahepatic Disorders in Youths

Giacomo Pozzoli 1,2, Hany E. Marei 3, Asma Althani 4, Alma Boninsegna 5, Patrizia Casalbore 6, Lionel NJL. Marlier 7, Giulia Lanzilli 7, Manuela Zonfrillo 7, Giovanna Petrucci 1, Bianca Rocca 1, Pierluigi Navarra 1, 2, Alessandro Sgambato 5 and Carlo Cenciarelli 7
Aspirin Inhibits Cancer Stem Cells properties and growth of Glioblastoma multiforme through Rb1 Pathway Modulation

Pozzoli G 1,2, Petrucci G 1, Navarra P 1,2, Marei HE 3, Cenciarelli C 4
Aspirin inhibits proliferation and promotes differentiation of neuroblastoma cells via p21Waf1 protein up-regulation and Rb1 pathway modulation.

Pacifico L1, Osborn JF2, Bonci E3, Pierimarchi P4, Chiesa C4.
Association between vitamin D levels and nonalcoholic fatty liver disease: potential confounding variables.

Luigia Cristino 1, Tiziana Bisogno 2, Vincenzo Di Marzo 1,3,4
Cannabinoids and the expanded endocannabinoid system in neurological disorders

1 Arriga, Roberto; 2 Caratelli, Sara; 2 Lanzilli, Giulia; 2 Ottaviani, Alessio; 2 Cenciarelli, Carlo; 3 Sconocchia, Tommaso; 2 Spagnoli, Giulio C.; 4 Iezzi, Giandomenica; 1 Roselli, Mario; 1 Lauro, Davide; 1 Coppola, Andrea; 5 Dotti, Gianpietro; 6 Ferrone, Soldano; 2 Sconocchia, Giuseppe
CD16-158-valine chimeric receptor T cells overcome the resistance of KRAS-mutated colorectal carcinoma cells to cetuximab

Petrosino, Maria; Pasquo, Alessandra; Novak, Leonore; Toto, Angelo; Gianni, Stefano; Mantuano, Elide; Veneziano, Liana; Minicozzi, Velia; Pastore, Annalisa; Puglisi, Rita; Capriotti, Emidio; Chiaraluce, Roberta; Consalvi, Valerio
Characterization of human frataxin missense variants in cancer tissues

Crema A. 1, Ledda M. 1, Fioretti D. 1, Lolli MG. 1, Sanchez M. 2, Carico E. 3, Marchese R. 4, Rinaldi M. 1, Lisi A. 1.
Combination of cord blood-derived human hepatic progenitors and hepatogenic factors strongly improves recovery after acute liver injury in mice through modulation of the Wnt/?-catenin signaling

Kowalski, Marek L.; Agache, Ioana; Bavbek, Sevim; Bakirtas, Arzu; Blanca, Miguel; Bochenek, Gra?yna; Bonini, Matteo; Heffler, Enrico; Klimek, Ludger; Laidlaw, Tanya M.; Mullol, Joaquim; Ni?ankowska-Mogilnicka, Ewa; Park, Hae Sim; Sanak, Marek; Sanchez-Borges, Mario; Sanchez-Garcia, Silvia; Scadding, Glenis; Taniguchi, Masami; Torres, Maria J.; White, Andrew A.; Wardzy?ska, Aleksandra
Diagnosis and management of NSAID-Exacerbated Respiratory Disease (N-ERD)--a EAACI position paper

Soligo M (1), Albini M (1), Bertoli FL (1), Marzano V (2), Protto V (1), Bracci-Laudiero L (1-3), Minnone G (3), De Benedetti F (3), Chiaretti A (4), Mantuano E (1), Manni L (1)
Different responses of PC12 cells to different pro-nerve growth factor protein variants

Giacovazzo G.; Bisogno T.; Piscitelli F.; Verde R.; Oddi S.; Maccarrone M.; Coccurello R.
Different Routes to Inhibit Fatty Acid Amide Hydrolase: Do All Roads Lead to the Same Place?

Protto V, Soligo M, De Stefano ME, Farioli-Vecchioli S, Marlier LNJL, Nisticò R, Manni L.
Electroacupuncture in rats normalizes the diabetes-induced alterations in the septo-hippocampal cholinergic system

Negri G.; Magini P.; Milani D.; Crippa M.; Biamino E.; Piccione M.; Sotgiu S.; Perria C.; Vitiello G.; Frontali M.; Boni A.; Di Fede E.; Gandini M.C.; Colombo E.A.; Bamshad M.J.; Nickerson D.A.; Smith J.D.; Loddo I.; Finelli P.; Seri M.; Pippucci T.; Larizza L.; Gervasini C.
Exploring by whole exome sequencing patients with initial diagnosis of Rubinstein-Taybi syndrome: the interconnections of epigenetic machinery disorders

Di Costanzo A.; Pacifico L.; Chiesa C.; Perla F.M.; Ceci F.; Angeloni A.; D'Erasmo L.; Di Martino M.; Arca M.
Genetic and metabolic predictors of hepatic fat content in a cohort of Italian children with obesity

Limongi D.; Baldelli S.; Checconi P.; Marcocci M.; De Chiara G.; Fraternale A.; Magnani M.; Ciriolo M.R.; Palamara A.T.
GSH-C4 Acts as Anti-inflammatory Drug in Different Models of Canonical and Cell Autonomous Inflammation Through NF?B Inhibition

Li Puma D.D.; Piacentini R.; Leone L.; Gironi K.; Marcocci M.E.; De Chiara G.; Palamara A.T.; Grassi C.
Herpes Simplex Virus Type-1 Infection Impairs Adult Hippocampal Neurogenesis via Amyloid-? Protein Accumulation

Guido Carloni 1, Daniela Fioretti 1, Monica Rinaldi 1, Antonio Ponzetto 2
Heterogeneity and coexistence of oncogenicmechanisms involved in HCV-associated B-cell lymphomas

Di Bonito P 1, Valerio G 2, Licenziati MR 3, Miraglia Del Giudice E 4, Baroni MG 5, Morandi A 6, Maffeis C 6, Campana G 3, Spreghini MR 7, Di Sessa A 4, Morino G 7, Crinò A 7, Chiesa C 8, Pacifico L 9, Manco M 10.
High uric acid, reduced glomerular filtration rate and non-alcoholic fatty liver in young people with obesity.

Hany E. Marei 1,+,* , Patrizia Casalbore 2,+, Asmaa Althani 3, Valentina Coccè 4, Carlo Cenciarelli 5, Giulio Alessandri 6, Anna T. Brini 4,7, Eugenio Parati 6, Gianpietro Bondiolotti 8 and Augusto Pessina 4
Human Olfactory Bulb Neural Stem Cells (Hu-OBNSCs) Can Be Loaded with Paclitaxel and Used to Inhibit Glioblastoma Cell Growth

Di Bonito P1, Valerio G2, Pacifico L3, Chiesa C4, Invitti C5, Morandi A6, Licenziati MR7, Manco M8, Giudice EMD9, Baroni MG10, Loche S11, Tornese G12, Franco F13, Maffeis C14, de Simone G15; CARITALY Study group; on the behalf of the Childhood Obesity Study Group of the Italian Society of Pediatric Endocrinology, Diabetology.
Impact of the 2017 Blood Pressure Guidelines by the American Academy of Pediatrics in overweight/obese youth.

Collu, Roberto; Scherma, Maria; Piscitelli, Fabiana; Giunti, Elisa; Satta, Valentina; Castelli, Maria P.; Verde, Roberta; Fratta, Walter; Bisogno, Tiziana; Fadda, Paola
Impaired brain endocannabinoid tone in the activity-based model of anorexia nervosa

Caratelli S1, Arriga R2, Sconocchia T3, Ottaviani A1, Lanzilli G1, Pastore D2, Cenciarelli C1, Venditti A4, Del Principe MI4, Lauro D2, Landoni E5, Du H5, Savoldo B5, Ferrone S6, Dotti G5, Sconocchia G1.
In vitro elimination of epidermal growth factor receptor-overexpressing cancer cells by CD32A-chimeric receptor T cells in combination with cetuximab or panitumumab

Aureli, Anna; Canossi, Angelica; Del Beato, Tiziana; Novelli, Giorgio; Buonomo, Oreste; Papola, Franco; Sconocchia, Giuseppe
INFLUENCE OF HLA-KIR AND FCGR3A GENES ON BREAST CANCER DEVELOPMENT AND PROGRESSION

Corbett, Mark A.; Kroes, Thessa; Veneziano, Liana; Bennett, Mark F.; Florian, Rahel; Schneider, Amy L.; Coppola, Antonietta; Licchetta, Laura; Franceschetti, Silvana; Suppa, Antonio; Wenger, Aaron; Mei, Davide; Pendziwiat, Manuela; Kaya, Sabine; Delledonne, Massimo; Straussberg, Rachel; Xumerle, Luciano; Regan, Brigid; Crompton, Douglas; van Rootselaar, Anne-Fleur; Correll, Anthony; Catford, Rachael; Bisulli, Francesca; Chakraborty, Shreyasee; Baldassari, Sara; Tinuper, Paolo; Barton, Kirston; Carswell, Shaun; Smith, Martin; Berardelli, Alfredo; Carroll, Renee; Gardner, Alison; Friend, Kathryn L.; Blatt, Ilan; Iacomino, Michele; Di Bonaventura, Carlo; Striano, Salvatore; Buratti, Julien; Keren, Boris; Nava, Caroline; Forlani, Sylvie; Rudolf, Gabrielle; Hirsch, Edouard; Leguern, Eric; Labauge, Pierre; Balestrini, Simona; Sander, Josemir W.; Afawi, Zaid; Helbig, Ingo; Ishiura, Hiroyuki; Tsuji, Shoji; Sisodiya, Sanjay M.; Casari, Giorgio; Sadleir, Lynette G.; van Coller, Riaan; Tijssen, Marina A. J.; Klein, Karl Martin; van den Maagdenberg, Arn M. J. M.; Zara, Federico; Guerrini, Renzo; Berkovic, Samuel F.; Pippucci, Tommaso; Canafoglia, Laura; Bahlo, Melanie; Striano, Pasquale; Scheffer, Ingrid E.; Brancati, Francesco; Depienne, Christel; Gecz, Jozef
Intronic ATTTC repeat expansions in STARD7 in fam ilial adult myoclonic epilepsy linked to chromosome 2

Costa G.; Porceddu P.F.; Serra M.; Casu M.A.; Schiano V.; Napolitano F.; Pinna A.; Usiello A.; Morelli M.
Lack of rhes increases mdma-induced neuroinflammation and dopamine neuron degeneration: Role of gender and age

Scarabino D (1), Veneziano L (2), Peconi M (3), Frontali M (2), Mantuano E (2), Corbo RM (4).
Leukocyte telomere shortening in Huntington's disease.

Natalia Battista, Monica Bari and Tiziana Bisogno
N-Acyl Amino Acids: Metabolism, Molecular Targets, and Role in Biological Processes

Di Costanzo A.; Pacifico L.; D'Erasmo L.; Polito L.; Martino M.D.; Perla F.M.; Iezzi L.; Chiesa C.; Arca M.
Nonalcoholic Fatty Liver Disease (NAFLD), But not Its Susceptibility Gene Variants, Influences the Decrease of Kidney Function in Overweight/Obese Children

Marianna Gabriella Rispoli1, Vincenzo Di Stefano1, Elide Mantuano2 and Maria Vittoria De Angelis3
Novel missense mutation in the ATP1A2 gene associated with atypical sporapedic hemiplegic migraine

Fabbrizio P1, Apolloni S2, Bianchi A2, Salvatori I2, Valle C2,3, Lanzuolo C2,4, Bendotti C1, Nardo G1, Volonté C2,5.
P2X7 activation enhances skeletal muscle metabolism and regeneration in SOD1G93A mouse model of amyotrophic lateral sclerosis.

1)Chiesa Claudio; 2)Andreoli Gian Marco; 1,2) Pacifico Lucia
Pediatric nonalcoholic fatty liver disease

Pfaar O.; Agache I.; de Blay F.; Bonini S.; Chaker A.M.; Durham S.R.; Gawlik R.; Hellings P.W.; Jutel M.; Kleine-Tebbe J.; Klimek L.; Kopp M.V.; Nandy A.; Rabin R.L.; van Ree R.; Renz H.; Roberts G.; Salapatek A.-M.; Schmidt-Weber C.B.; Shamji M.H.; Sturm G.J.; Virchow J.C.; Wahn U.; Willers C.; Zieglmayer P.; Akdis C.A.
Perspectives in allergen immunotherapy: 2019 and beyond

Baldacci S.1; Simoni M.1; Maio S.1; Angino A.1; Martini F.1; Sarno G.1; Cerrai S.1; Silvi P.1; Pala A.P.2; Bresciani M.1; Paggiaro P.3; Viegi G.1,4 and the ARGA Collaborative Group
Prescriptive adherence to GINA guidelines and asthma control: An Italian cross sectional study in general practice

Agache I.; Annesi-Maesano I.; Bonertz A.; Branca F.; Cant A.; Fras Z.; Ingenrieth F.; Namazova-Baranova L.; Odemyr M.; Spanevello A.; Vieths S.; Yorgancioglu A.; Alvaro-Lozano M.; Barber Hernandez D.; Chivato T.; Del Giacco S.; Diamant Z.; Eguiluz-Gracia I.; van Wijk R.G.; Gevaert P.; Graessel A.; Hellings P.; Hoffmann-Sommergruber K.; Jutel M.; Lau S.; Lauerma A.; Maria Olaguibel J.; O'Mahony L.; Ozdemir C.; Palomares O.; Pfaar O.; Sastre J.; Scadding G.; Schmidt-Weber C.; Schmid-Grendelmeier P.; Shamji M.; Skypala I.; Spinola M.; Spranger O.; Torres M.; Vereda A.; Bonini S.
Prioritizing research challenges and funding for allergy and asthma and the need for translational research--The European Strategic Forum on Allergic Diseases

Maria Pia Fuggetta ,1 Maria Rita Migliorino,2 Serena Ricciardi,2 Giorgia Osman,2 Daniela Iacono,2 Alvaro Leone,3 Alessandra Lombardi,2 Giampietro Ravagnan,1 Stefania Greco,2 Daniele Remotti,3 and Maria Concetta Pucci Romano4
Prophylactic Dermatologic Treatment of Afatinib-Induced Skin Toxicities in Patients with Metastatic Lung Cancer: A Pilot Study

Hany E. Marei 1, Asma Althani 2, Thomas Caceci 3, Roberto Arriga 4, Tommaso Sconocchia 5, Alessio Ottaviani 6, Giulia Lanzilli 6, Mario Roselli 4, Sara Caratelli 6, Carlo Cenciarelli 6*, Giuseppe Sconocchia 6*
Recent perspective on CAR and Fcgamma-CR T cell immunotherapy for cancers: Preclinical evidence versus clinical outcomes

De Chiara G.; Piacentini R.; Fabiani M.; Mastrodonato A.; Marcocci M.E.; Limongi D.; Napoletani G.; Protto V.; Coluccio P.; Celestino I.; Li Puma D.D.; Grassi C.; Palamara A.T.
Recurrent herpes simplex virus-1 infection induces hallmarks of neurodegeneration and cognitive deficits in mice

Anna Maria Berghella, Anna Aureli, Angelica Canossi, Tiziana Del Beato, Alessia Colanardi, Patrizia Pellegrini
Redox, immune and genetic biomarker system for personalized treatments in colorectal cancer

1,2)Lucia Pacifico, 1)Francesco Massimo Perla, 2)Claudio Chiesa
Sarcopenia and nonalcoholic fatty liver disease: a causal relationship

Platella C1, Raucci U1, Rega N2, D'Atri S3, Levati L3, Roviello GN4, Fuggetta MP5, Musumeci D6, Montesarchio D1.
Shedding light on the interaction of polydatin and resveratrol with G-quadruplex and duplex DNA: a biophysical, computational and biological approach.

Alessandrino, F. Fregnan, M. Biagiotti, L. Muratori, G.A. Bassani, G. Ronchi V. Vincoli, Pasquale Pierimarchi, S. Geuna , G. Freddi
SilkBridge: a novel biomimetic and biocompatible silk-based nerve conduit Biomaterials Science

Jensen-Jarolim E1, Bachmann M2, Bonini S3, Jacobsen L4, Jutel M5,6, Klimek L7, Mahler V8, Mösges R9, Moingeon P10, O Hehir RE11, Palomares O12, Pfaar O13, Renz H14, Rhyner C15, Roth-Walter F16, Rudenko M17, Savolainen J18, Schmidt-Weber C19, Traidl-Hoffmann C20, Kündig T21.
State-of-the-art in marketed adjuvants and formulations in Allergen Immunotherapy: a position paper of the European Academy of Allergy and Clinical Immunology (EAACI)

Sferrazza G.; Nicotera G.; Pierimarchi P.
Suspected adverse drug reactions (ADRs) trends in older Italian patients: an analysis from the National Pharmacovigilance Network

Piscitelli F.; Coccurello R.; Totaro A.; Leuti A.; Giacovazzo G.; Verde R.; Rossi E.; Podaliri Vulpiani M.; Ferri N.; Giacominelli Stuffler R.; Di Marzo V.; Oddi S.; Bisogno T.; Maccarrone M.
Targeted Lipidomics Investigation of N-acylethanolamines in a Transgenic Mouse Model of AD: A Longitudinal Study

Sciamanna I.; Serafino A.; Shapiro J.A.; Spadafora C.
The active role of spermatozoa in transgenerational inheritance

Di Bonito, Procolo; Licenziati, Maria Rosaria; Baroni, Marco G.; Maffeis, Claudio; Morandi, Anita; Manco, Melania; del Giudice, Emanuele Miraglia; Di Sessa, Anna; Campana, Giuseppina; Moio, Nicola; Gilardini, Luisa; Chiesa, Claudio; Pacifico, Lucia; de Simone, Giovanni; Valerio, Giuliana; Driul, D.; Forziato, C.; Loche, S.; Tornese, G.
The American Academy of Pediatrics hypertension guidelines identify obese youth at high cardiovascular risk among individuals non-hypertensive by the European Society of Hypertension guidelines

Laura Brandolini & Marta Grannonico & Gianluca Bianchini & Alessia Colanardi & Pierluigi Sebastiani & Antonella Paladini & Alba Piroli & Marcello Allegretti & Giustino Varrassi & Silvia Di Loreto
The Novel C5aR Antagonist DF3016A Protects Neurons Against Ischemic Neuroinflammatory Injury

Costa, G.; Serra, M.; Pintori, N.; Casu, M. A.; Zanda, M. T.; Murtas, D.; De Luca, M. Antonietta; Simola. N.; Fattore, L.
The novel psychoactive substance methoxetamine induces persistent behavioral abnormalities and neurotoxicity in rats

Serrano, Alessia; Apolloni, Savina; Rossi, Simona; Lattante, Serena; Sabatelli, Mario; Peric, Mina; Andjus, Pavle; Michetti, Fabrizio; Carri, Maria Teresa; Cozzolino, Mauro; D'Ambrosi, Nadia
The S100A4 Transcriptional Inhibitor Niclosamide Reduces Pro-Inflammatory and Migratory Phenotypes of Microglia: Implications for Amyotrophic Lateral Sclerosis

Pizzato Scomazzon S.; Riccio A.; Santopolo S.; Lanzilli G.; Coccia M.; Rossi A.; Santoro M.G.
The Zinc-Finger AN1-Type Domain 2a Gene Acts as a Regulator of Cell Survival in Human Melanoma: Role of E3-Ligase cIAP2

Alessandrino, Antonio; Chiarini, Anna; Biagiotti, Marco; Dal Pra, Ilaria; Bassani, Giulia A.; Vincoli, Valentina; Settembrini, Piergiorgio; Pierimarchi, Pasquale; Freddi, Giuliano; Armato, Ubaldo
Three-Layered Silk Fibroin Tubular Scaffold for the Repair and Regeneration of Small Caliber Blood Vessels: From Design to in vivo Pilot Tests

Aya Elgamal,1 Asmaa Althani A,2 Ahmed Abd-Elmaksoud,1 Mohammed Kassab,3 Amany Farag,1 Samah Lashen,1 Mahmoud M Gabr,4 Mahmoud M Zakaria,4 Mohga M Alissawi,4 Hossam El-Din Ali Ismail,5 Ahmed Abd El Galil,5 Thomas Caceci,6 Carlo Cenciarelli C,7,* and Hany E Marei1,*
Xeno-free trans-differentiation of adipose tissue-derived mesenchymal stem cells into glial and neuronal cells

 
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