Abstract:
To study the molecular evolution of the lectin family in Lima bean, we characterized the polypeptides belonging to this multigene family and cloned the genes belonging to the Mesoamerican gene pool. The latter gene pool contains components similar to those of the Andean gene pool, namely an á-amylase inhibitor like (AIL), an arcelin-like (ARL) lectin and the less abundant Lima bean lectin (LBL). These proteins originate from an ancestor gene of the lectin type which duplicated to yield the lectin gene and the progenitor of ARL and AIL. In this species, ARL represents an evolutionary intermediate form that precedes AIL. Phylogenetic analysis support an Andean origin for Lima bean. The molecular evolutionary studies were extended to the genes of common bean and demonstrated that true lectin genes and tha ancestor of lectin-related genes the result of a duplication event that occurred before speciation. Lima and common bean followed different evolutionary pathways and in the latter species a second duplication event occurred that gave rise, in Mesomerican wild genotypes, to arcelin genes.

Note:
ISI Journal Citation Reports Ranking: 2000 : Impact Factor 3,592

Descrizione sintetica del prodotto:
Studi biochimici ed evolutivi su una famiglia multigenica che codifica per proteine lectino-simili coinvolte nei meccanismi di resistenza ad insetti fitofagi nel fagiolo di Lima

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