SKIM LEAN "Systematic lab Knowledge Integration for Management of Lipid Excess in high-risk pAtieNts (DSB.AD007.143)

Thematic area

Biomedical sciences

Project area

Structure responsible for the research project

Institute of clinical physiology (IFC)

Project manager

MARIAGIOVANNA TRIVELLA
Phone number: 050 3152730
Email: trivella@ifc.cnr.it

Abstract

SKIM LEAN goal is to exploit Electronic Health Records (EHRs) to integrate knowledge derived from routine laboratory tests with background analysis of clinical databases for the identification and early referral to specialist care, where appropriate, of patients with hypercholesterolemia, who may be inadequately controlled according to their cardiovascular (CV) risk level. SKIM LEAN addresses gaps in care that may occur through the lack of coordination between primary and specialist care, incomplete adherence to clinical guidelines, or poor patient compliance to physician's prescriptions because of comorbidities or drug side effects. By close collaboration between clinical and information technology partners, SKIM LEAN will fully exploit the value of big data deriving from EHR and filter this knowledge using clinically-derived algorithms to risk-stratify patients. SKIM LEAN will merge educational strategies to foster awareness and empowerment of subjects at CV risk and support clinical practice through an integrated care pathway with iterative knowledge extraction from EHR.
IFC-CNR activities: Clinical-ICT interface, website referral coordination, protocol drafting, reports.

Goals

The Key Objectives of the project include the acquisition of new knowledge and the improvement of process and outcome indicators as follows:
- To assess prevalence of uncontrolled hypercholesterolemia in Niguarda Hospital catchment area among patients discharged from hospital after CV events or interventional/surgical procedures and community-dwelling outpatients who are otherwise at high risk.
- To improve clinical competence and patient empowerment through a two-tiered educational website for GPs and patients.
- To scan laboratory data for clues to comorbidities, causes of secondary hypercholesterolemia, side effects and/or interference with cholesterol-lowering agents.To streamline referral of uncontrolled high-risk or very high-risk patients from GP to specialist outpatient management through a shared care pathway.
- To increased proportion of patients at high- or very-high CV risk who achieve target LDL cholesterol (LDL-C) levels.

Start date of activity

01/01/2017

Keywords

Heterozygous Familial Hypercholesterolaemia (HeFH), Statin non-responders, Electronic Health Records (EHR)

Last update: 20/05/2024